دانلود کتاب Protein-Protein Interactions: Methods and Applications

عنوان فارسی :

دانلود کتاب تعاملات پروتئین-پروتئین: روش ها و برنامه های کاربردی

عنوان انگلیسی :

Protein-Protein Interactions: Methods and Applications

زبان : English

موضوع : Biology->Biotechnology

نویسندگان : Robert C. Liddington (auth.) Haian Fu (eds.)

ناشر : Humana Press

ISBN (شابک) : 9781588291202, 1588291200

تعداد صفحات : 532\501

سال نشر : 2004     ویرایش : 1

حجم : 5 MB       فرمت : pdf

قیمت : 4000 تومان

خلاصه کتاب به فارسی (ترجمه خودکار و سیستمی) و خارجی:
تولد اولین معجزه زندگی است که در هیبت و رمز و راز پوشیده شده است. با این حال ، مرگ ، فیل ضرب المثل در اتاق است - واقعی و گنگ ، اما نادیده گرفته شده است. مرگ سزاوار اعتبار بیشتری از آن است که دریافت می کند. همراه با تولد ، مرگ ظرفی را تشکیل می دهد که زندگی ما را شکل می دهد. اگر تصدیق کنیم ، مرگ چارچوبی برای بررسی زندگی و زندگی آگاهانه ، معنادار و با محبت تر ارائه می دهد.

خلاصه کتاب به زبان اصلی :

Proteins continuously interact with each other to determine cell fate. Consequently, an examination of just when such protein-protein interactions occur and how they are controlled is essential for understanding the molecular mechanism of biological processes, elucidating the molecular basis of diseases, and identifying potential targets for therapeutic interventions. In Protein-Protein Interactions: Methods and Applications, leading experts describe in detail their highly successful biochemical, biophysical, genetic, and computational techniques for studying these interactions. Their readily reproducible methods demonstrate how to identify protein interaction partners, qualitatively or quantitatively measure protein-protein interactions, monitor protein-protein interactions as they occur in living cells, and determine interaction interfaces. The techniques described utilize a variety of cutting-edge technologies, including surface plasmon resonance (SRP), fluorescence resonance energy transfer (FRET), fluorescence polarization (FP), isothermal titration calorimetry (ITC), circular dichroism (CD), protein fragment complementation assays (PCA), various two-hybrid systems, and proteomics- and bioinformatics-based approaches, such as the Scansite program for computational analysis. Each time-tested protocol includes a background introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, Protein-Protein Interactions: Methods and Applications offers both beginning and experienced investigators a full range of the powerful tools needed for deciphering how proteins interact to form biological networks, as well as for unraveling protein-protein interactions in disease in the search for novel therapeutic targets.

فهرست :



Table of contents :
Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Front Matter....Pages 3-14
Front Matter....Pages 15-31
Front Matter....Pages 33-33
Front Matter....Pages 35-54
Front Matter....Pages 55-77
Back Matter....Pages 79-91
....Pages 93-111




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